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Ma Huang Lian Qiao Chi Xiao Dou Tang (麻黄连翘赤小豆汤) — Damp-Heat Jaundice

On this page

  1. Overview
  2. TCM pattern
  3. Key herbs
  4. Formula actions
  5. Conditions treated
  6. Cautions

Overview

Ma Huang Lian Qiao Chi Xiao Dou Tang — the “Ephedra, Forsythia and Adzuki Bean Decoction” — is from Zhang Zhongjing’s Shang Han Lun. Originally prescribed for jaundice with an exterior pattern still unresolved, the formula combines a Wind-Cold surface-releasing action (Ma Huang) with Damp-Heat clearance (Lian Qiao, Chi Xiao Dou). Modern dermatologists use it widely for acute itchy skin eruptions with both surface obstruction and Damp-Heat — the classical “Wind-Damp-Heat” skin pattern where Heat cannot escape because the surface is closed.

I prescribe Ma Huang Lian Qiao Chi Xiao Dou Tang as part of bespoke herbal formulas from pharmaceutical-grade granules sourced from Sun Ten in Taiwan.

TCM pattern

Ma Huang Lian Qiao Chi Xiao Dou Tang is prescribed for Damp-Heat with an unresolved exterior:

  • Yang-type jaundice with fever, aversion to cold, no sweat
  • Acute itchy red rash, possibly weeping
  • Slight oedema, especially of upper body or face
  • Dark yellow urine
  • Chest oppression, slight cough[10]
  • Tongue — red, yellow greasy coat
  • Pulse — floating, slippery, rapid

Key herbs

  1. Ma Huang (Hb. Ephedrae, 6-9g) — releases the exterior; opens the Lung; promotes urination
  2. Lian Qiao (Fr. Forsythiae, 6-15g) — clears Heat and resolves toxin
  3. Chi Xiao Dou (adzuki bean, 9-30g) — drains Damp; resolves toxin; reduces oedema
  4. Xing Ren (Sm. Armeniacae, 6-9g) — descends Lung Qi; assists Ma Huang
  5. Sang Bai Pi ((Cx. Mori, 6-9g), 6-9g) — drains Lung Heat and promotes urination
  6. Gan Cao (Rx. Glycyrrhizae, 3-6g) — harmonises
  7. Sheng Jiang (Rz. Zingiberis Recens, 3-6g), Da Zao (Fr. Jujube, 3-6g) — harmonise the Stomach

Formula actions

  1. Releases the exterior
  2. Clears Damp-Heat from the interior
  3. Promotes urination; reduces jaundice and oedema
  4. Resolves Heat-toxin in the skin

Conditions treated

  1. Acute hepatitis with Yang-type jaundice and surface symptoms (alongside conventional care)
  2. Acute eczema flare with weeping itchy lesions
  3. Acute urticaria with Damp-Heat pattern
  4. Acute glomerulonephritis with oedema, dark urine, no sweat (with conventional care)
  5. Cholestatic itch with jaundice
  6. Acute contact dermatitis
  7. Acute drug rash with Damp-Heat pattern

Cautions

Contains Ma Huang — contraindicated in hypertension[19], hyperthyroidism[6], anxiety[4], glaucoma, prostatic hypertrophy, and with MAO inhibitors or sympathomimetics.

Acute hepatitis with rising bilirubin or coagulopathy requires urgent hepatology assessment.

Severe widespread skin reactions (Stevens-Johnson, DRESS) require emergency care.

Not appropriate for Yin-deficient patterns, chronic deficiency or pure interior Heat without surface obstruction.

Always consult a qualified Chinese herbalist registered with the RCHM.

Prefer to be treated from home? Chinese herbal medicine online consultations are available throughout the UK and worldwide.

References

[4] Lin Y, Cai S, Wang T, Zhuang T, Huang T, Yu X, et al. Evaluation of the Safety and Efficacy of Xiao Yao San as a Treatment for Anxiety: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2022;2022:1319592. https://doi.org/10.1155/2022/1319592. PMID: 35432568.

[6] Liu Y, Cheng L, Yan G, Gu J, Lyu Z, Ding J. Effectiveness and potential mechanism of Jiawei-Xiaoyao-San for hyperthyroidism: a systematic review. Front Endocrinol (Lausanne). 2023 Sep 18;14:1241962. https://doi.org/10.3389/fendo.2023.1241962. PMID: 37780612.

[10] Lee B, Kwon CY, Suh HW, Kim YJ, Kim KI, Lee BJ, Lee JH. Herbal medicine for the treatment of chronic cough: a systematic review and meta-analysis. Front Pharmacol. 2023 Oct 17;14:1230604. https://doi.org/10.3389/fphar.2023.1230604. PMID: 37920213.

[19] Wang J, Xiong X, Liu W. Tianma Gouteng Yin as Adjunctive Treatment for Essential Hypertension: A Systematic Review of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2013;2013:706125. https://doi.org/10.1155/2013/706125. PMID: 23710230.

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